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Estrogen deficiency impairs integrin α(v)β(3)-mediated mechanosensation by osteocytes and alters osteoclastogenic paracrine signalling
The integrin α(v)β(3) has been shown to play an important role in osteocyte mechanotransduction. It has been reported that there are fewer β(3) integrin-containing cells in osteoporotic bone cells. Osteocytes cultured in vitro under estrogen deficient conditions demonstrate altered mechanotransducti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420496/ https://www.ncbi.nlm.nih.gov/pubmed/30874595 http://dx.doi.org/10.1038/s41598-019-41095-3 |