Cargando…
The MurG glycosyltransferase provides an oligomeric scaffold for the cytoplasmic steps of peptidoglycan biosynthesis in the human pathogen Bordetella pertussis
Peptidoglycan is a major component of the bacterial cell wall and thus a major determinant of cell shape. Its biosynthesis is initiated by several sequential reactions catalyzed by cytoplasmic Mur enzymes. Mur ligases (MurC, -D, -E, and -F) are essential for bacteria, metabolize molecules not presen...
Autores principales: | Laddomada, Federica, Miyachiro, Mayara M., Jessop, Matthew, Patin, Delphine, Job, Viviana, Mengin-Lecreulx, Dominique, Le Roy, Aline, Ebel, Christine, Breyton, Cécile, Gutsche, Irina, Dessen, Andréa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420597/ https://www.ncbi.nlm.nih.gov/pubmed/30874582 http://dx.doi.org/10.1038/s41598-019-40966-z |
Ejemplares similares
-
The essential peptidoglycan glycosyltransferase MurG forms a complex with proteins involved in lateral envelope growth as well as with proteins involved in cell division in Escherichia coli
por: Mohammadi, Tamimount, et al.
Publicado: (2007) -
Putative hexameric glycosyltransferase functional unit revealed by the crystal structure of Acinetobacter baumannii MurG
por: Jung, Kyoung Ho, et al.
Publicado: (2021) -
Architecture and genomic arrangement of the MurE–MurF bacterial cell wall biosynthesis complex
por: Shirakawa, Karina T., et al.
Publicado: (2023) -
Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics
por: Trunkfield, Amy E., et al.
Publicado: (2010) -
Specificity Determinants for Lysine Incorporation in Staphylococcus aureus Peptidoglycan as Revealed by the Structure of a MurE Enzyme Ternary Complex
por: Ruane, Karen M., et al.
Publicado: (2013)