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Restoration of high-sensitivity and adapting vision with a cone opsin
Inherited and age-related retinal degenerative diseases cause progressive loss of rod and cone photoreceptors, leading to blindness, but spare downstream retinal neurons, which can be targeted for optogenetic therapy. However, optogenetic approaches have been limited by either low light sensitivity...
Autores principales: | Berry, Michael H., Holt, Amy, Salari, Autoosa, Veit, Julia, Visel, Meike, Levitz, Joshua, Aghi, Krisha, Gaub, Benjamin M., Sivyer, Benjamin, Flannery, John G., Isacoff, Ehud Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420663/ https://www.ncbi.nlm.nih.gov/pubmed/30874546 http://dx.doi.org/10.1038/s41467-019-09124-x |
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