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Targeting RNA helicase DDX3 in stem cell maintenance and teratoma formation
DDX3 is an RNA helicase that has antiapoptotic properties, and promotes proliferation and transformation. Besides the role of DDX3 in transformed cells, there is evidence to indicate that DDX3 expression is at its highest levels during early embryonic development and is also expressed in germ cells...
Autores principales: | Kerr, Candace L., Bol, Guus M., Vesuna, Farhad, Raman, Venu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420792/ https://www.ncbi.nlm.nih.gov/pubmed/30899416 http://dx.doi.org/10.18632/genesandcancer.187 |
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