Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

PD-L1 and PD-L2 are ligands for the PD-1 immune inhibiting checkpoint that can be induced in tumors by interferon exposure, leading to immune evasion. This process is important for immunotherapy based on PD-1 blockade. We examined the specific molecules involved in interferon-induced signaling that...

Descripción completa

Detalles Bibliográficos
Autores principales: Garcia-Diaz, Angel, Shin, Daniel Sanghoon, Moreno, Blanca Homet, Saco, Justin, Escuin-Ordinas, Helena, Rodriguez, Gabriel Abril, Zaretsky, Jesse M., Sun, Lu, Hugo, Willy, Wang, Xiaoyan, Parisi, Giulia, Saus, Cristina Puig, Torrejon, Davis Y., Graeber, Thomas G., Comin-Anduix, Begonya, Hu-Lieskovan, Siwen, Damoiseaux, Robert, Lo, Roger S., Ribas, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420824/
https://www.ncbi.nlm.nih.gov/pubmed/28494868
http://dx.doi.org/10.1016/j.celrep.2017.04.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420824/
https://www.ncbi.nlm.nih.gov/pubmed/28494868
http://dx.doi.org/10.1016/j.celrep.2017.04.031

Ejemplares similares