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Metabolic heterogeneity underlies reciprocal fates of T(H)17 cell stemness and plasticity
A defining feature of adaptive immunity is the development of long-lived memory T cells to curtail infection. Recent studies have identified a unique stem-like T cell subset in exhausted CD8(+) T cells in chronic infection(1–3), but it remains unclear whether CD4(+) T cell subsets with similar featu...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420879/ https://www.ncbi.nlm.nih.gov/pubmed/30568299 http://dx.doi.org/10.1038/s41586-018-0806-7 |