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Link between the unfolded protein response and dysregulation of mitochondrial bioenergetics in Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder affecting more than 47.5 million people worldwide. Metabolic impairments are common hallmarks of AD, and amyloid-β (Aβ) peptide and hyperphosphorylated tau protein—the two foremost histopathological signs of AD—have been implicated...

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Detalles Bibliográficos
Autores principales:	Poirier, Yannik, Grimm, Amandine, Schmitt, Karen, Eckert, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420888/ https://www.ncbi.nlm.nih.gov/pubmed/30683981 http://dx.doi.org/10.1007/s00018-019-03009-4

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