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Maternal Cardiac Function after Normal Delivery, Preeclampsia, and Eclampsia: A Prospective Study

INTRODUCTION: The aim of this study is to assess maternal cardiac function in the postpartum period, after 2 and 6 months in the parturient with preeclampsia and eclampsia. MATERIALS AND METHODS: Prospective study: 90 postpartum women after preeclampsia and eclampsia and 55 patients after an uncompl...

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Autores principales: Timokhina, Elena, Kuzmina, Tatiana, Strizhakov, Alexander, Pitskhelauri, Elena, Ignatko, Irina, Belousova, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420982/
https://www.ncbi.nlm.nih.gov/pubmed/30941219
http://dx.doi.org/10.1155/2019/9795765
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author Timokhina, Elena
Kuzmina, Tatiana
Strizhakov, Alexander
Pitskhelauri, Elena
Ignatko, Irina
Belousova, Vera
author_facet Timokhina, Elena
Kuzmina, Tatiana
Strizhakov, Alexander
Pitskhelauri, Elena
Ignatko, Irina
Belousova, Vera
author_sort Timokhina, Elena
collection PubMed
description INTRODUCTION: The aim of this study is to assess maternal cardiac function in the postpartum period, after 2 and 6 months in the parturient with preeclampsia and eclampsia. MATERIALS AND METHODS: Prospective study: 90 postpartum women after preeclampsia and eclampsia and 55 patients after an uncomplicated pregnancy. The parameters of maternal hemodynamics were recorded on days 1, 3, 5, 9, and 14 of postpartum period, after 2 and 6 months. The cardiac parameters were assessed. RESULTS: PE is accompanied by increased peripheral vascular resistance. The indicator of vascular resistance, SVR, is elevated for both mild and severe PE. With mild PE, a significant increase in SVR is observed up to 5 days of postpartum period, with severe PE/E up to 9 days. We found that in case of severe PE, SVR remains elevated to 6 months after delivery. The parameters of the contractile function of the heart (ESV, EDV, SV, SI, CO, СI, MVCF) were significantly decreased: with mild PE up to 5-9 days, with severe up to 9-14 days of puerperia. ESV, SV, SI, CO, and CI remain low with severe PE up to 6 months. The revealed decreasing of contractile function of the heart is a sign of asymptomatic heart failure. CONCLUSIONS: The hemodynamics of the puerperas after PE and E is characterized by impaired contractility of the myocardium and an increase in the indices of peripheral resistance. The degree of deviation in the parameters of cardiac hemodynamics and vascular resistance depended on the severity of hypertensive complications of pregnancy.
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spelling pubmed-64209822019-04-02 Maternal Cardiac Function after Normal Delivery, Preeclampsia, and Eclampsia: A Prospective Study Timokhina, Elena Kuzmina, Tatiana Strizhakov, Alexander Pitskhelauri, Elena Ignatko, Irina Belousova, Vera J Pregnancy Research Article INTRODUCTION: The aim of this study is to assess maternal cardiac function in the postpartum period, after 2 and 6 months in the parturient with preeclampsia and eclampsia. MATERIALS AND METHODS: Prospective study: 90 postpartum women after preeclampsia and eclampsia and 55 patients after an uncomplicated pregnancy. The parameters of maternal hemodynamics were recorded on days 1, 3, 5, 9, and 14 of postpartum period, after 2 and 6 months. The cardiac parameters were assessed. RESULTS: PE is accompanied by increased peripheral vascular resistance. The indicator of vascular resistance, SVR, is elevated for both mild and severe PE. With mild PE, a significant increase in SVR is observed up to 5 days of postpartum period, with severe PE/E up to 9 days. We found that in case of severe PE, SVR remains elevated to 6 months after delivery. The parameters of the contractile function of the heart (ESV, EDV, SV, SI, CO, СI, MVCF) were significantly decreased: with mild PE up to 5-9 days, with severe up to 9-14 days of puerperia. ESV, SV, SI, CO, and CI remain low with severe PE up to 6 months. The revealed decreasing of contractile function of the heart is a sign of asymptomatic heart failure. CONCLUSIONS: The hemodynamics of the puerperas after PE and E is characterized by impaired contractility of the myocardium and an increase in the indices of peripheral resistance. The degree of deviation in the parameters of cardiac hemodynamics and vascular resistance depended on the severity of hypertensive complications of pregnancy. Hindawi 2019-03-03 /pmc/articles/PMC6420982/ /pubmed/30941219 http://dx.doi.org/10.1155/2019/9795765 Text en Copyright © 2019 Elena Timokhina et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Timokhina, Elena
Kuzmina, Tatiana
Strizhakov, Alexander
Pitskhelauri, Elena
Ignatko, Irina
Belousova, Vera
Maternal Cardiac Function after Normal Delivery, Preeclampsia, and Eclampsia: A Prospective Study
title Maternal Cardiac Function after Normal Delivery, Preeclampsia, and Eclampsia: A Prospective Study
title_full Maternal Cardiac Function after Normal Delivery, Preeclampsia, and Eclampsia: A Prospective Study
title_fullStr Maternal Cardiac Function after Normal Delivery, Preeclampsia, and Eclampsia: A Prospective Study
title_full_unstemmed Maternal Cardiac Function after Normal Delivery, Preeclampsia, and Eclampsia: A Prospective Study
title_short Maternal Cardiac Function after Normal Delivery, Preeclampsia, and Eclampsia: A Prospective Study
title_sort maternal cardiac function after normal delivery, preeclampsia, and eclampsia: a prospective study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420982/
https://www.ncbi.nlm.nih.gov/pubmed/30941219
http://dx.doi.org/10.1155/2019/9795765
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