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Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway
IgE is secreted by plasma cells (PCs) and is central to allergic disease. Using an ex vivo tonsil B cell culture system, which mimics the Th2 responses in vivo, we have recently characterized the development pathway of human IgE-expressing PCs. In this system, as in mice, we reported the predisposit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421273/ https://www.ncbi.nlm.nih.gov/pubmed/30915071 http://dx.doi.org/10.3389/fimmu.2019.00402 |