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Differential Requirement of Cd8 Enhancers E8(I) and E8(VI) in Cytotoxic Lineage T Cells and in Intestinal Intraepithelial Lymphocytes
CD8 expression in T lymphocytes is tightly regulated by the activity of at least six Cd8 enhancers (E8(I)-E8(VI)), however their complex developmental stage-, subset-, and lineage-specific interplays are incompletely understood. Here we analyzed ATAC-seq data on the Immunological Genome Project data...
Autores principales: | Gülich, Alexandra Franziska, Preglej, Teresa, Hamminger, Patricia, Alteneder, Marlis, Tizian, Caroline, Orola, Maria Jonah, Muroi, Sawako, Taniuchi, Ichiro, Ellmeier, Wilfried, Sakaguchi, Shinya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421288/ https://www.ncbi.nlm.nih.gov/pubmed/30915074 http://dx.doi.org/10.3389/fimmu.2019.00409 |
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