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A Novel Small Molecule Which Increases Osteoprotegerin Expression and Protects Against Ovariectomy-Related Bone Loss in Rats
The ratio of osteoprotegerin (OPG) to the receptor activator of NF-κB ligand (RANKL) is a key determinant in the regulation of bone metabolism. The study was performed to screen novel anti-osteoporotic drugs regulating OPG/RANKL ratio and evaluate their effect on bone metabolism. According to the sc...
Autores principales: | Han, Xiaowan, Gong, Shiqiang, Li, Ni, Wang, Xiao, Liu, Peng, Xu, Yanni, He, Xiaobo, Jiang, Wei, Si, Shuyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421503/ https://www.ncbi.nlm.nih.gov/pubmed/30914947 http://dx.doi.org/10.3389/fphar.2019.00103 |
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