Dependence on Myb expression is attenuated in myeloid leukaemia with N-terminal CEBPA mutations

Mutations at the N- or C-terminus of C/EBPα are frequent in acute myeloid leukaemia (AML) with normal karyotype. Here, we investigate the role of the transcription factor Myb in AMLs driven by different combinations of CEBPA mutations. Using knockdown of Myb in murine cell lines modelling the spectr...

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Detalles Bibliográficos
Autores principales: Volpe, Giacomo, Cauchy, Pierre, Walton, David S, Ward, Carl, Blakemore, Daniel, Bayley, Rachael, Clarke, Mary L, Schmidt, Luisa, Nerlov, Claus, Garcia, Paloma, Dumon, Stéphanie, Grebien, Florian, Frampton, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421631/
https://www.ncbi.nlm.nih.gov/pubmed/30877232
http://dx.doi.org/10.26508/lsa.201800207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421631/
https://www.ncbi.nlm.nih.gov/pubmed/30877232
http://dx.doi.org/10.26508/lsa.201800207

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