The FATZO mouse, a next generation model of type 2 diabetes, develops NAFLD and NASH when fed a Western diet supplemented with fructose

BACKGROUND: Metabolic disorders such as insulin resistance, obesity, and hyperglycemia are prominent risk factors for the development of non-alcoholic fatty liver disease (NAFLD)/steatohepatitis (NASH). Dietary rodent models employ high fat, high cholesterol, high fructose, methionine/choline defici...

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Detalles Bibliográficos
Autores principales: Sun, Gao, Jackson, Charles V., Zimmerman, Karen, Zhang, Li-Kun, Finnearty, Courtney M., Sandusky, George E., Zhang, Guodong, Peterson, Richard G., Wang, Yi-Xin (Jim)
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421686/
https://www.ncbi.nlm.nih.gov/pubmed/30885145
http://dx.doi.org/10.1186/s12876-019-0958-4

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