Cargando…

7,8-Dihydroxyflavone Protects Nigrostriatal Dopaminergic Neurons from Rotenone-Induced Neurotoxicity in Rodents

7,8-Dihydroxyflavone (7,8-DHF) is thought to be a promising therapeutic agent for various neurodegenerative diseases. The major purpose of this study was to investigate the neuroprotective effects of 7,8-DHF on the rotenone-induced motor deficit of Parkinson's disease. Nine-month-old rats were...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nie, Shuke, Ma, Kai, Sun, Mingkuan, Lee, Matthew, Tan, Yang, Chen, Guiqin, Zhang, Zhentao, Zhang, Zhaohui, Cao, Xuebing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421741/ https://www.ncbi.nlm.nih.gov/pubmed/30944722 http://dx.doi.org/10.1155/2019/9193534

Ejemplares similares

TRH Analog, Taltirelin Protects Dopaminergic Neurons From Neurotoxicity of MPTP and Rotenone
por: Zheng, Cong, et al.
Publicado: (2018)

Treadmill exercise alleviates nigrostriatal dopaminergic loss of neurons and fibers in rotenone-induced Parkinson rats
por: Shin, Mal-Soon, et al.
Publicado: (2017)

7,8-Dihydroxyflavone Ameliorates Cognitive Impairment by Inhibiting Expression of Tau Pathology in ApoE-Knockout Mice
por: Tan, Yang, et al.
Publicado: (2016)

A Current Review of Cypermethrin-Induced Neurotoxicity and Nigrostriatal Dopaminergic Neurodegeneration
por: Singh, Anand Kumar, et al.
Publicado: (2012)

3D printed elastic hydrogel conduits with 7,8-dihydroxyflavone release for peripheral nerve repair
por: Wu, Wenbi, et al.
Publicado: (2023)

miR‐30b protects nigrostriatal dopaminergic neurons from MPP(+)‐induced neurotoxicity via SNCA
por: Shen, Yu‐fei, et al.
Publicado: (2020)

Neuroprotective Effects of 7, 8-dihydroxyflavone on Midbrain Dopaminergic Neurons in MPP(+)-treated Monkeys
por: He, Jingjing, et al.
Publicado: (2016)

Methanolic Extract of Boswellia serrata Gum Protects the Nigral Dopaminergic Neurons from Rotenone-Induced Neurotoxicity
por: Shadfar, Sina, et al.
Publicado: (2022)

7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress
por: Cho, Suk Ju, et al.
Publicado: (2019)

Stereotaxical Infusion of Rotenone: A Reliable Rodent Model for Parkinson's Disease
por: Xiong, Nian, et al.
Publicado: (2009)

7,8-Dihydroxyflavone Enhances Cue-Conditioned Alcohol Reinstatement in Rats
por: Hogarth, Samuel J., et al.
Publicado: (2020)

Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP(+) and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway
por: Guo, Xingfang, et al.
Publicado: (2019)

7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis
por: Xue, Fan, et al.
Publicado: (2021)

Synapse‐selective rapid potentiation of hippocampal synaptic transmission by 7,8‐dihydroxyflavone
por: Kobayashi, Katsunori, et al.
Publicado: (2018)

Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase
por: Liu, Yun-Chin, et al.
Publicado: (2020)

The TrkB agonist, 7,8-dihydroxyflavone, impairs fracture healing in mice
por: Johnstone, Maddison R., et al.
Publicado: (2021)

Atrazine Causes Autophagy- and Apoptosis-Related Neurodegenerative Effects in Dopaminergic Neurons in the Rat Nigrostriatal Dopaminergic System
por: Song, Xiao-Yao, et al.
Publicado: (2015)

Neurotoxicity of the pesticide rotenone on neuronal polarization: a mechanistic approach
por: Bisbal, Mariano, et al.
Publicado: (2019)

Metabolic protection by the dietary flavonoid 7,8-dihydroxyflavone requires an intact gut microbiome
por: Sharma, Priyanka, et al.
Publicado: (2022)

Rescue of Long-Term Spatial Memory by 7,8-Dihydroxyflavone in Mice with Reduced Oligodendrogenesis
por: Rawlings-Mortimer, Florence, et al.
Publicado: (2023)

Naringin: A Protector of the Nigrostriatal Dopaminergic Projection
por: Jung, Un Ju, et al.
Publicado: (2014)

Effects of LRRK2 Inhibitors on Nigrostriatal Dopaminergic Neurotransmission
por: Qin, Qi, et al.
Publicado: (2016)

7,8-Dihydroxyflavone protects neurons against oxygen-glucose deprivation induced apoptosis and activates the TrkB/Akt pathway
por: Zhou, Qinxiang, et al.
Publicado: (2022)

Effect of 7,8-Dihydroxyflavone as an Antioxidant on In Vitro Maturation of Oocytes and Development of Parthenogenetic Embryos in Pigs
por: CHOI, Ji-Yei, et al.
Publicado: (2013)

Low-dose 7,8-Dihydroxyflavone Administration After Status Epilepticus Prevents Epilepsy Development
por: Guarino, Annunziata, et al.
Publicado: (2022)

7,8-Dihydroxyflavone and Neuropsychiatric Disorders: A Translational Perspective from the Mechanism to Drug Development
por: Yang, Shaojie, et al.
Publicado: (2022)

Bilateral Implantation of Shear Stress Modifier in ApoE Knockout Mouse Induces Cognitive Impairment and Tau Abnormalities
por: Nie, Shuke, et al.
Publicado: (2018)

Cerebrotendinous xanthomatosis: a comprehensive review of pathogenesis, clinical manifestations, diagnosis, and management
por: Nie, Shuke, et al.
Publicado: (2014)

Apelin-13 Protects Dopaminergic Neurons against Rotenone—Induced Neurotoxicity through the AMPK/mTOR/ULK-1 Mediated Autophagy Activation
por: Chen, Peng, et al.
Publicado: (2020)

Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit
por: Pham, Anh H., et al.
Publicado: (2012)

No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models
por: Sastry, Namratha, et al.
Publicado: (2015)

Beneficial effect of estrogen on nigrostriatal dopaminergic neurons in drug-naïve postmenopausal Parkinson’s disease
por: Lee, Yang Hyun, et al.
Publicado: (2019)

Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson’s disease: removing axonal debris
por: Morales, Ingrid, et al.
Publicado: (2021)

Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum
por: Du, Huan, et al.
Publicado: (2015)

Antidyskinetic Effects of MEK Inhibitor Are Associated with Multiple Neurochemical Alterations in the Striatum of Hemiparkinsonian Rats
por: Chen, Guiqin, et al.
Publicado: (2017)

Nigrostriatal dopaminergic depletion increases static orofacial allodynia
por: Dieb, Wisam, et al.
Publicado: (2016)

Exploring the Molecular Interactions of 7,8-Dihydroxyflavone and Its Derivatives with TrkB and VEGFR2 Proteins
por: Chitranshi, Nitin, et al.
Publicado: (2015)

7,8-Dihydroxyflavone activates Nrf2/HO-1 signaling pathways and protects against osteoarthritis
por: Cai, Dawei, et al.
Publicado: (2019)

Sex-Dependent Effects of 7,8-Dihydroxyflavone on Metabolic Health Are Associated with Alterations in the Host Gut Microbiome
por: Sharma, Priyanka, et al.
Publicado: (2021)

7,8-dihydroxyflavone enhances long-term spatial memory and alters brain volume in wildtype mice
por: Rawlings-Mortimer, Florence, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f2t2afpgb4ffnh7eqbmm0npui1