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Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice

BACKGROUND: Statins are recommended for cardiovascular protection for people with diabetes (high-risk groups). This study aimed to evaluate the gap between the guidelines of statin utilization and clinical practice among outpatients with type 2 diabetes regarding the patient's age and gender, t...

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Autores principales: Hammad, Mohamed Anwar, Syed Sulaiman, Syed Azhar, Aziz, Nor Azizah, Mohamed Noor, Dzul Azri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421885/
https://www.ncbi.nlm.nih.gov/pubmed/30988683
http://dx.doi.org/10.4103/jrms.JRMS_100_18
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author Hammad, Mohamed Anwar
Syed Sulaiman, Syed Azhar
Aziz, Nor Azizah
Mohamed Noor, Dzul Azri
author_facet Hammad, Mohamed Anwar
Syed Sulaiman, Syed Azhar
Aziz, Nor Azizah
Mohamed Noor, Dzul Azri
author_sort Hammad, Mohamed Anwar
collection PubMed
description BACKGROUND: Statins are recommended for cardiovascular protection for people with diabetes (high-risk groups). This study aimed to evaluate the gap between the guidelines of statin utilization and clinical practice among outpatients with type 2 diabetes regarding the patient's age and gender, to assess if this preventive drug is being satisfactorily utilized or not. MATERIALS AND METHODS: In this cross-sectional study, patients aged <40 or >75 years, pregnant patients, and patients with type 1 diabetes, human immunodeficiency virus, or liver cirrhosis were excluded. Demographics, laboratory parameters, and prevalence of exposure to statin therapy were evaluated. This study was guided by the 2013 American College of Cardiology/American Heart Association cholesterol guidelines. IBM SPSS software was used for data management. RESULTS: The study cohort involved 576 patients, with age being 58.3 ± 8.9 years. There were 50.5% of females and 49.5% of males. Overall 81.1% of patients aged 58.8 ± 8.8 years were statin users and 18.9% of patients aged 56.2 ± 9 years were statin nonusers. About 83.2% of females and 78.9% of males were prescribed statins. Statin medications included simvastatin 79.2%, atorvastatin 11.6%, lovastatin 5.8%, rosuvastatin 2.1%, and pravastatin 1.3%. Statin users’ and nonusers’ adherence was 56.5%, and 41.3% (P = 0.004), respectively. The adherence to medication plan of females and males was 55.7% and 51.6%, respectively (P = 0.004). CONCLUSION: Patients with diabetes who are at high risk of cardiovascular events, exposure to statin treatment is significantly less than perfect position both in females and males. Nearly one-fifth of the patients with type 2 diabetes are not using statins despite therapeutic necessities.
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spelling pubmed-64218852019-04-15 Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice Hammad, Mohamed Anwar Syed Sulaiman, Syed Azhar Aziz, Nor Azizah Mohamed Noor, Dzul Azri J Res Med Sci Original Article BACKGROUND: Statins are recommended for cardiovascular protection for people with diabetes (high-risk groups). This study aimed to evaluate the gap between the guidelines of statin utilization and clinical practice among outpatients with type 2 diabetes regarding the patient's age and gender, to assess if this preventive drug is being satisfactorily utilized or not. MATERIALS AND METHODS: In this cross-sectional study, patients aged <40 or >75 years, pregnant patients, and patients with type 1 diabetes, human immunodeficiency virus, or liver cirrhosis were excluded. Demographics, laboratory parameters, and prevalence of exposure to statin therapy were evaluated. This study was guided by the 2013 American College of Cardiology/American Heart Association cholesterol guidelines. IBM SPSS software was used for data management. RESULTS: The study cohort involved 576 patients, with age being 58.3 ± 8.9 years. There were 50.5% of females and 49.5% of males. Overall 81.1% of patients aged 58.8 ± 8.8 years were statin users and 18.9% of patients aged 56.2 ± 9 years were statin nonusers. About 83.2% of females and 78.9% of males were prescribed statins. Statin medications included simvastatin 79.2%, atorvastatin 11.6%, lovastatin 5.8%, rosuvastatin 2.1%, and pravastatin 1.3%. Statin users’ and nonusers’ adherence was 56.5%, and 41.3% (P = 0.004), respectively. The adherence to medication plan of females and males was 55.7% and 51.6%, respectively (P = 0.004). CONCLUSION: Patients with diabetes who are at high risk of cardiovascular events, exposure to statin treatment is significantly less than perfect position both in females and males. Nearly one-fifth of the patients with type 2 diabetes are not using statins despite therapeutic necessities. Medknow Publications & Media Pvt Ltd 2019-02-25 /pmc/articles/PMC6421885/ /pubmed/30988683 http://dx.doi.org/10.4103/jrms.JRMS_100_18 Text en Copyright: © 2019 Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Hammad, Mohamed Anwar
Syed Sulaiman, Syed Azhar
Aziz, Nor Azizah
Mohamed Noor, Dzul Azri
Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice
title Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice
title_full Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice
title_fullStr Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice
title_full_unstemmed Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice
title_short Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice
title_sort prescribing statins among patients with type 2 diabetes: the clinical gap between the guidelines and practice
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421885/
https://www.ncbi.nlm.nih.gov/pubmed/30988683
http://dx.doi.org/10.4103/jrms.JRMS_100_18
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