Use of transethosomes for enhancing the transdermal delivery of olmesartan medoxomil: in vitro, ex vivo, and in vivo evaluation

INTRODUCTION AND AIM: Olmesartan medoxomil (OLM) is an antihypertensive drug with low oral bioavailability due to extensive first-pass metabolism. This study aimed to prepare transetho somes (TEs) for enhancing the transdermal delivery of OLM to avoid its oral problems. METHODS: TE formulae were pre...

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Detalles Bibliográficos
Autores principales: Albash, Rofida, Abdelbary, Aly A, Refai, Hanan, El-Nabarawi, Mohamed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421897/
https://www.ncbi.nlm.nih.gov/pubmed/30936696
http://dx.doi.org/10.2147/IJN.S196771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421897/
https://www.ncbi.nlm.nih.gov/pubmed/30936696
http://dx.doi.org/10.2147/IJN.S196771

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