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Paradoxical effects of cellular senescence-inhibited gene involved in hepatocellular carcinoma migration and proliferation by ERK pathway and mesenchymal-like markers

BACKGROUND: Cellular senescence-inhibited gene (CSIG) strongly prolongs the progression of replicative senescence. However, roles and mechanisms of CSIG in tumor progression have not been studied widely. METHODS: Roles of CSIG in migration and proliferation of SMMC7721 and Huh7 cells were analyzed b...

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Detalles Bibliográficos
Autores principales: Cheng, Qian, Tong, Tan-jun, Li, Zhao, Hu, Shi-hua, Chen, Ding-bao, Wang, Si-qi, Zhu, Ji-ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421901/
https://www.ncbi.nlm.nih.gov/pubmed/30936720
http://dx.doi.org/10.2147/OTT.S188449