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NAT2 variants and toxicity related to anti-tuberculosis agents: a systematic review and meta-analysis

BACKGROUND: Tuberculosis (TB) patients receiving anti-tuberculosis treatment may experience serious adverse drug reactions (ADRs) such as hepatotoxicity. Variants of the N-acetyltransferase 2 (NAT2) gene may increase the risk of experiencing such toxicity events. OBJECTIVE: To provide a comprehensiv...

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Detalles Bibliográficos
Autores principales:	Richardson, M., Kirkham, J., Dwan, K., Sloan, D. J., Davies, G., Jorgensen, A. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union Against Tuberculosis and Lung Disease 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421944/ https://www.ncbi.nlm.nih.gov/pubmed/30871660 http://dx.doi.org/10.5588/ijtld.18.0324

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