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Plasmodium chabaudi AS Infection Induces CD4(+) Th1 Cells and Foxp3(+)T-bet(+) Regulatory T Cells That Express CXCR3 and Migrate to CXCR3 Ligands
Control and elimination of blood-stage Plasmodium chabaudi AS infection requires CD4(+) Th1 cells that secrete IFN-γ and T follicular help (Tfh) cells together with B cell production of antibody. Foxp3(+) regulatory T cells (Tregs) are also crucial to protect the host from immunopathology and severe...
Autores principales: | Berretta, Floriana, Piccirillo, Ciriaco A., Stevenson, Mary M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422055/ https://www.ncbi.nlm.nih.gov/pubmed/30915078 http://dx.doi.org/10.3389/fimmu.2019.00425 |
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