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Super-enhancers: novel target for pancreatic ductal adenocarcinoma

Super-enhancers (SEs) are unique areas of the genome which drive high-level of transcription and play a pivotal role in the cell physiology. Previous studies have established several important genes in cancer as SE-driven oncogenes. It is likely that oncogenes may hack the resident tissue regenerati...

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Detalles Bibliográficos
Autores principales: Ghosh, Chandrayee, Paul, Santanu, Dandawate, Prasad, Gunewardena, Sumedha S., Subramaniam, Dharmalingam, West, Cameron, Anant, Shrikant, Dhar, Animesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422180/
https://www.ncbi.nlm.nih.gov/pubmed/30899425
http://dx.doi.org/10.18632/oncotarget.26704