Cargando…
Differential localizations of protein phosphatase 1 isoforms determine their physiological function in the heart
Protein phosphatase 1 isoforms α, β, and γ (PP1α, PP1β, and PP1γ) are highly homologous in the catalytic domains but have distinct subcellular localizations. In this study, we utilized both primary cell culture and knockout mice to investigate the isoform-specific roles of PP1s in the heart. In both...
Autores principales: | Liu, Ruijie, Miller, Christian, D’Annibale, Christiana, Vo, Kimberly, Jacobs, Ashley |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422231/ https://www.ncbi.nlm.nih.gov/pubmed/30721967 http://dx.doi.org/10.1093/abbs/gmy171 |
Ejemplares similares
-
Substrate recognition determinants of human eIF2α phosphatases
por: Hodgson, George, et al.
Publicado: (2021) -
De novo synthesis of protein phosphatase 1A, magnesium dependent, alpha isoform (PPM1A) during oocyte maturation
por: Chuderland, Dana, et al.
Publicado: (2012) -
Paradoxes in dynamic stability of mechanical systems: investigating the causes and detecting the nonlinear behaviors
por: Luongo, Angelo, et al.
Publicado: (2016) -
Differential isoform expression of Allergin‐1 during acute and chronic inflammation
por: Geerdink, Ruben J., et al.
Publicado: (2022) -
The protein phosphatase activity of PTEN is essential for regulating neural stem cell differentiation
por: Lyu, Jingwen, et al.
Publicado: (2015)