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Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study

Acute respiratory infections (ARIs) are a leading cause of under-five mortality globally. In Kenya, the reported prevalence of respiratory syncytial virus (RSV) infections in single-centre studies has varied widely. Our study sought to determine the prevalence of RSV infection in children admitted w...

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Autores principales: Le Geyt, Jacqueline, Hauck, Stephanie, Lee, Mark, Mackintosh, Jennifer, Slater, Jessica, Razon, Duke, Williams, Bhanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422239/
https://www.ncbi.nlm.nih.gov/pubmed/30957029
http://dx.doi.org/10.1136/bmjpo-2018-000409
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author Le Geyt, Jacqueline
Hauck, Stephanie
Lee, Mark
Mackintosh, Jennifer
Slater, Jessica
Razon, Duke
Williams, Bhanu
author_facet Le Geyt, Jacqueline
Hauck, Stephanie
Lee, Mark
Mackintosh, Jennifer
Slater, Jessica
Razon, Duke
Williams, Bhanu
author_sort Le Geyt, Jacqueline
collection PubMed
description Acute respiratory infections (ARIs) are a leading cause of under-five mortality globally. In Kenya, the reported prevalence of respiratory syncytial virus (RSV) infections in single-centre studies has varied widely. Our study sought to determine the prevalence of RSV infection in children admitted with ARI fulfilling the WHO criteria for bronchiolitis. This was a prospective cross-sectional prevalence study in five hospitals across central and highland Kenya from April to June 2015. Two hundred and thirty-four participants were enrolled. The overall RSV positive rate was 8.1%, which is lower than in previous Kenyan studies. RSV-positive cases were on average 5 months younger than RSV-negative cases.
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spelling pubmed-64222392019-04-05 Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study Le Geyt, Jacqueline Hauck, Stephanie Lee, Mark Mackintosh, Jennifer Slater, Jessica Razon, Duke Williams, Bhanu BMJ Paediatr Open Research Letters Acute respiratory infections (ARIs) are a leading cause of under-five mortality globally. In Kenya, the reported prevalence of respiratory syncytial virus (RSV) infections in single-centre studies has varied widely. Our study sought to determine the prevalence of RSV infection in children admitted with ARI fulfilling the WHO criteria for bronchiolitis. This was a prospective cross-sectional prevalence study in five hospitals across central and highland Kenya from April to June 2015. Two hundred and thirty-four participants were enrolled. The overall RSV positive rate was 8.1%, which is lower than in previous Kenyan studies. RSV-positive cases were on average 5 months younger than RSV-negative cases. BMJ Publishing Group 2019-03-04 /pmc/articles/PMC6422239/ /pubmed/30957029 http://dx.doi.org/10.1136/bmjpo-2018-000409 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Research Letters
Le Geyt, Jacqueline
Hauck, Stephanie
Lee, Mark
Mackintosh, Jennifer
Slater, Jessica
Razon, Duke
Williams, Bhanu
Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study
title Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study
title_full Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study
title_fullStr Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study
title_full_unstemmed Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study
title_short Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study
title_sort respiratory syncytial virus prevalence in children admitted to five kenyan district hospitals: a cross-sectional study
topic Research Letters
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422239/
https://www.ncbi.nlm.nih.gov/pubmed/30957029
http://dx.doi.org/10.1136/bmjpo-2018-000409
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