Novel scaffolds for modulation of TRPV1 identified with pharmacophore modeling and virtual screening

AIM: The transient receptor potential vanilloid type 1 (TRPV1) is responsible for pain perception in the peripheral nervous system (PNS). TRPV1 is thus considered a versatile target for development of non-opioid analgesics. RESULTS: Pharmacophore-based clustering of a publicly available data set of...

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Detalles Bibliográficos
Autores principales: Goldmann, Daria, Pakfeifer, Peter, Hering, Steffen, Ecker, Gerhard F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422283/
https://www.ncbi.nlm.nih.gov/pubmed/25826358
http://dx.doi.org/10.4155/fmc.14.168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422283/
https://www.ncbi.nlm.nih.gov/pubmed/25826358
http://dx.doi.org/10.4155/fmc.14.168

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