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Mysteries in embryonic development: How can errors arise so frequently at the beginning of mammalian life?

Chromosome segregation errors occur frequently during female meiosis but also in the first mitoses of mammalian preimplantation development. Such errors can lead to aneuploidy, spontaneous abortions, and birth defects. Some of the mechanisms underlying these errors in meiosis have been deciphered bu...

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Detalles Bibliográficos
Autores principales: Schneider, Isabell, Ellenberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422315/
https://www.ncbi.nlm.nih.gov/pubmed/30840627
http://dx.doi.org/10.1371/journal.pbio.3000173