Cargando…

The prion 2018 round tables (I): the structure of PrP(Sc)

Understanding the structure of PrP(Sc) is without doubt a sine qua non to understand not only PrP(Sc) propagation, but also critical features of that process such as the strain phenomenon and transmission barriers. While elucidation of the PrP(Sc) structure has been full of difficulties, we now have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baskakov, Ilia V., Caughey, Byron, Requena, Jesús R., Sevillano, Alejandro M., Surewicz, Witold K., Wille, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Commentaries and Views
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422368/ https://www.ncbi.nlm.nih.gov/pubmed/30646817 http://dx.doi.org/10.1080/19336896.2019.1569450

Ejemplares similares

The Structure of PrP(Sc) Prions
por: Wille, Holger, et al.
Publicado: (2018)

Small Protease Sensitive Oligomers of PrP(Sc) in Distinct Human Prions Determine Conversion Rate of PrP(C)
por: Kim, Chae, et al.
Publicado: (2012)

Identifying critical sites of PrP(c)-PrP(Sc) interaction in prion-infected cells by dominant-negative inhibition
por: Taguchi, Yuzuru, et al.
Publicado: (2013)

Inflammatory response of microglia to prions is controlled by sialylation of PrP(Sc)
por: Srivastava, Saurabh, et al.
Publicado: (2018)

The Prion 2018 round tables (II): Aβ, tau, α-synuclein… are they prions, prion-like proteins, or what?
por: Eraña, Hasier
Publicado: (2019)

Sialylation of Prion Protein Controls the Rate of Prion Amplification, the Cross-Species Barrier, the Ratio of PrP(Sc) Glycoform and Prion Infectivity
por: Katorcha, Elizaveta, et al.
Publicado: (2014)

Heterogeneity of Abnormal Prion Protein (PrP(Sc)) in Murine Scrapie Prions Determined by PrP(Sc)-Specific Monoclonal Antibodies
por: USHIKI-KAKU, Yuko, et al.
Publicado: (2013)

Infectivity-associated PrP(Sc) and disease duration-associated PrP(Sc) of mouse BSE prions
por: Miyazawa, Kohtaro, et al.
Publicado: (2015)

Propagation of PrP(Sc) in mice reveals impact of aggregate composition on prion disease pathogenesis
por: Chang, Sheng Chun, et al.
Publicado: (2023)

Assessment of Strain-Specific PrP(Sc) Elongation Rates Revealed a Transformation of PrP(Sc) Properties during Protein Misfolding Cyclic Amplification
por: Gonzalez-Montalban, Nuria, et al.
Publicado: (2012)

Exploration of the Main Sites for the Transformation of Normal Prion Protein (PrP(C)) into Pathogenic Prion Protein (PrP(sc))
por: Liu, Xi-Lin, et al.
Publicado: (2017)

PrP(Sc) formation and clearance as determinants of prion tropism
por: Shikiya, Ronald A., et al.
Publicado: (2017)

Recombinant PrP(Sc) shares structural features with brain-derived PrP(Sc): Insights from limited proteolysis
por: Sevillano, Alejandro M., et al.
Publicado: (2018)

Anti-Prion Drug mPPIg5 Inhibits PrP(C) Conversion to PrP(Sc)
por: McCarthy, James M., et al.
Publicado: (2013)

Post-translational modifications in PrP expand the conformational diversity of prions in vivo
por: Aguilar-Calvo, Patricia, et al.
Publicado: (2017)

The Octarepeat Region of the Prion Protein Is Conformationally Altered in PrP(Sc)
por: Yam, Alice Y., et al.
Publicado: (2010)

PrP(Sc)-Specific Antibodies with the Ability to Immunodetect Prion Oligomers
por: Tayebi, Mourad, et al.
Publicado: (2011)

Prion protein and susceptibility to kainate-induced seizures: Genetic pitfalls in the use of PrP knockout mice
por: Striebel, James F, et al.
Publicado: (2013)

PK-sensitive PrP(Sc) Is Infectious and Shares Basic Structural Features with PK-resistant PrP(Sc)
por: Sajnani, Gustavo, et al.
Publicado: (2012)

Transgenic mice recapitulate the phenotypic heterogeneity of genetic prion diseases without developing prion infectivity: Role of intracellular PrP retention in neurotoxicity
por: Chiesa, Roberto, et al.
Publicado: (2016)

Glimepiride Reduces the Expression of PrP(C), Prevents PrP(Sc) Formation and Protects against Prion Mediated Neurotoxicity
por: Bate, Clive, et al.
Publicado: (2009)

A Camelid Anti-PrP Antibody Abrogates PrP(Sc) Replication in Prion-Permissive Neuroblastoma Cell Lines
por: Jones, Daryl Rhys, et al.
Publicado: (2010)

Heterogeneity of the Abnormal Prion Protein (PrP(Sc)) of the Chandler Scrapie Strain
por: Kasai, Kazuo, et al.
Publicado: (2013)

Glial activation in prion diseases is selectively triggered by neuronal PrP(Sc)
por: Lakkaraju, Asvin K. K., et al.
Publicado: (2022)

On the reactive states of astrocytes in prion diseases
por: Baskakov, Ilia V.
Publicado: (2021)

Analysis of Prion Strains by PrP(Sc) Profiling in Sporadic Creutzfeldt–Jakob Disease
por: Schoch, Gaby, et al.
Publicado: (2006)

PrP(Sc )spreading patterns in the brain of sheep linked to different prion types
por: Wemheuer, Wiebke M, et al.
Publicado: (2011)

Prion acute synaptotoxicity is largely driven by protease-resistant PrP(Sc) species
por: Foliaki, Simote Totauhelotu, et al.
Publicado: (2018)

Modeling PrP(Sc) Generation Through Deformed Templating
por: Spagnolli, Giovanni, et al.
Publicado: (2020)

Accumulation of Pathological Prion Protein PrP(Sc) in the Skin of Animals with Experimental and Natural Scrapie
por: Thomzig, Achim, et al.
Publicado: (2007)

How do PrP(Sc) Prions Spread between Host Species, and within Hosts?
por: Mabbott, Neil A.
Publicado: (2017)

Prion protein amino acid sequence influences formation of authentic synthetic PrP(Sc)
por: Block, Alyssa J., et al.
Publicado: (2023)

The N-Terminal Sequence of Prion Protein Consists an Epitope Specific to the Abnormal Isoform of Prion Protein (PrP(Sc))
por: Masujin, Kentaro, et al.
Publicado: (2013)

Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP
por: Sakudo, Akikazu, et al.
Publicado: (2015)

Prion Seeding Activities of Mouse Scrapie Strains with Divergent PrP(Sc) Protease Sensitivities and Amyloid Plaque Content Using RT-QuIC and eQuIC
por: Vascellari, Sarah, et al.
Publicado: (2012)

Disulfide-crosslink scanning reveals prion–induced conformational changes and prion strain–specific structures of the pathological prion protein PrP(Sc)
por: Taguchi, Yuzuru, et al.
Publicado: (2018)

The First Evaluation of Proteinase K-Resistant Prion Protein (PrP(Sc)) in Korean Appendix Specimens
por: Won, Sae-Young, et al.
Publicado: (2022)

Mammalian prion propagation in PrP transgenic Drosophila
por: Thackray, Alana M, et al.
Publicado: (2018)

Kosmotropic Anions Promote Conversion of Recombinant Prion Protein into a PrP(Sc)-Like Misfolded Form
por: Diaz-Espinoza, Rodrigo, et al.
Publicado: (2012)

Detection of Pathognomonic Biomarker PrP(Sc) and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases
por: Eraña, Hasier, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_20njfn93kocbnf0rc2f31vf8rs