Identification of neoantigen-specific T cells and their targets: implications for immunotherapy of head and neck squamous cell carcinoma

To develop a practically applicable method for T-cell receptor (TCR)-engineered T cell immunotherapy targeting neoantigens, we have been attempting to identify neoantigen-specific T cell receptors (TCRs) and establish TCR-engineered T cells in a 3–4-month period. In this study, we report the charact...

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Detalles Bibliográficos
Autores principales: Ren, Lili, Leisegang, Matthias, Deng, Boya, Matsuda, Tatsuo, Kiyotani, Kazuma, Kato, Taigo, Harada, Makiko, Park, Jae-Hyun, Saloura, Vassiliki, Seiwert, Tanguy, Vokes, Everett, Agrawal, Nishant, Nakamura, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422382/
https://www.ncbi.nlm.nih.gov/pubmed/30906664
http://dx.doi.org/10.1080/2162402X.2019.1568813

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