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Constitutively active BRS3 is a genuinely orphan GPCR in placental mammals
G protein–coupled receptors (GPCRs) play an important role in physiology and disease and represent the most productive drug targets. Orphan GPCRs, with their endogenous ligands unknown, were considered a source of drug targets and consequently attract great interest to identify their endogenous cogn...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422423/ https://www.ncbi.nlm.nih.gov/pubmed/30840614 http://dx.doi.org/10.1371/journal.pbio.3000175 |