Oral immunization of mice with a probiotic Lactobacillus casei constitutively expressing the α-toxoid induces protective immunity against Clostridium perfringens α-toxin

Clostridium perfringens α-toxin is one of the major virulence factors during C. perfringens infection, causing hemolysis of erythrocytes in various species. Here, genetically engineered Lactobacillus casei (pPG-α/L. casei 393) constitutively expressing the toxoid of C. perfringens α-toxin was genera...

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Detalles Bibliográficos
Autores principales: Gao, Xuwen, Ma, Yingying, Wang, Zhuo, Bai, Jing, Jia, Shuo, Feng, Baohua, Jiang, Yanping, Cui, Wen, Tang, Lijie, Li, Yijing, Wang, Li, Xu, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422513/
https://www.ncbi.nlm.nih.gov/pubmed/30806148
http://dx.doi.org/10.1080/21505594.2019.1582975

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