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Overlooked: Extrachromosomal DNA and Their Possible Impact on Whole Genome Sequencing
Extrachromosomal (ec) DNA in eukaryotic cells has been known for decades. The structures described range from linear double stranded (ds) DNA to circular dsDNA, distinct from mitochondrial (mt) DNA. The sizes of circular forms are described from some hundred base pairs (bp) up to more than 150 kbp....
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Penerbit Universiti Sains Malaysia
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422590/ https://www.ncbi.nlm.nih.gov/pubmed/30918452 http://dx.doi.org/10.21315/mjms2018.25.2.3 |