Cargando…

Role of the tumor microenvironment in pancreatic cancer

Pancreatic cancer remains a highly recalcitrant disease despite the development of systemic chemotherapies. New treatment options are thus urgently required. Dense stromal formation, so‐called “desmoplastic stroma,” plays controversial roles in terms of pancreatic cancer growth, invasion, and metast...

Descripción completa

Detalles Bibliográficos
Autores principales:	Murakami, Takashi, Hiroshima, Yukihiko, Matsuyama, Ryusei, Homma, Yuki, Hoffman, Robert M., Endo, Itaru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422798/ https://www.ncbi.nlm.nih.gov/pubmed/30923782 http://dx.doi.org/10.1002/ags3.12225

Ejemplares similares

The Tumor-Educated-Macrophage Increase of Malignancy of Human Pancreatic Cancer Is Prevented by Zoledronic Acid
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models
por: Murakami, Takashi, et al.
Publicado: (2019)

Essential updates 2019/2020: Surgical treatment of gallbladder cancer
por: Matsuyama, Ryusei, et al.
Publicado: (2021)

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Low Incidence of High-Grade Pancreatic Intraepithelial Neoplasia Lesions in a Crmp4 Gene–Deficient Mouse Model of Pancreatic Cancer
por: Yazawa, Keiichi, et al.
Publicado: (2020)

Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models
por: Murakami, Takashi, et al.
Publicado: (2015)

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model
por: Murakami, Takashi, et al.
Publicado: (2015)

Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models
por: Murakami, Takashi, et al.
Publicado: (2015)

Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant Patient Soft-Tissue Sarcoma in Nude Mice
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival
por: Oshi, Masanori, et al.
Publicado: (2021)

Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model
por: Murakami, Takashi, et al.
Publicado: (2016)

Fluorescence-Guided Surgery in Combination with UVC Irradiation Cures Metastatic Human Pancreatic Cancer in Orthotopic Mouse Models
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy
por: Hiroshima, Yukihiko, et al.
Publicado: (2016)

High-Mobility Group Box 1 expression predicts survival of patients after resection of adenocarcinoma of the ampulla of Vater
por: Murakami, Takashi, et al.
Publicado: (2019)

A case of triple digestive tract reconstruction in chronic pancreatitis complicated with bile ductal stenosis, duodenal stenosis, and portal vein stenosis: a case report
por: Abe, Yuka, et al.
Publicado: (2020)

Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations
por: Miyake, Kentaro, et al.
Publicado: (2018)

Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug
por: Murakami, Takashi, et al.
Publicado: (2016)

Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chemotherapy
por: Miyake, Kentaro, et al.
Publicado: (2018)

Neoadjuvant Therapy for Extrahepatic Biliary Tract Cancer: A Propensity Score-Matched Survival Analysis
por: Toyoda, Junya, et al.
Publicado: (2023)

Annexin A1 Expression Is Associated with Epithelial–Mesenchymal Transition (EMT), Cell Proliferation, Prognosis, and Drug Response in Pancreatic Cancer
por: Oshi, Masanori, et al.
Publicado: (2021)

The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing’s sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapy
por: Miyake, Kentaro, et al.
Publicado: (2017)

Role of the Intramural Vascular Network of the Extrahepatic Bile Duct for the Blood Circulation in the Recipient Extrahepatic Bile Duct Used for Duct-to-Duct-Biliary-Anastomosis in Living Donor Liver Transplantation
por: Yamaguchi, Naotaka, et al.
Publicado: (2022)

High Expression of NRF2 Is Associated with Increased Tumor-Infiltrating Lymphocytes and Cancer Immunity in ER-Positive/HER2-Negative Breast Cancer
por: Oshi, Masanori, et al.
Publicado: (2020)

Inflammation Is Associated with Worse Outcome in the Whole Cohort but with Better Outcome in Triple-Negative Subtype of Breast Cancer Patients
por: Oshi, Masanori, et al.
Publicado: (2020)

A Novel Four-Gene Score to Predict Pathologically Complete (R0) Resection and Survival in Pancreatic Cancer
por: Oshi, Masanori, et al.
Publicado: (2020)

Intra-Tumoral Angiogenesis Is Associated with Inflammation, Immune Reaction and Metastatic Recurrence in Breast Cancer
por: Oshi, Masanori, et al.
Publicado: (2020)

Tumor Microenvironment Role in Pancreatic Cancer Stem Cells
por: Galindo-Vega, Aaron, et al.
Publicado: (2023)

Impact of intramuscular adipose tissue content on short- and long-term outcomes of hepatectomy for colorectal liver metastasis: a retrospective analysis
por: Horii, Nobutoshi, et al.
Publicado: (2020)

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model
por: Murakami, Takashi, et al.
Publicado: (2016)

The maximum chemiluminescence intensity predicts severe neutropenia in gemcitabine-treated patients with pancreatic or biliary tract cancer
por: Goto, Koki, et al.
Publicado: (2018)

The role of TGF-β in the tumor microenvironment of pancreatic cancer
por: Luo, Qiang, et al.
Publicado: (2022)

The Unfolded Protein Response Is Associated with Cancer Proliferation and Worse Survival in Hepatocellular Carcinoma
por: Patel, Ankit, et al.
Publicado: (2021)

MUC1 Selectively Targets Human Pancreatic Cancer in Orthotopic Nude Mouse Models
por: Park, Jeong Youp, et al.
Publicado: (2015)

High G2M Pathway Score Pancreatic Cancer is Associated with Worse Survival, Particularly after Margin-Positive (R1 or R2) Resection
por: Oshi, Masanori, et al.
Publicado: (2020)

CD8 T Cell Score as a Prognostic Biomarker for Triple Negative Breast Cancer
por: Oshi, Masanori, et al.
Publicado: (2020)

Pancreatic cancer: disease dynamics, tumor biology and the role of the microenvironment
por: Ansari, Daniel, et al.
Publicado: (2018)

Role of the Tumor Microenvironment in Regulating Pancreatic Cancer Therapy Resistance
por: Deng, Daiyong, et al.
Publicado: (2022)

Plasmacytoid Dendritic Cell (pDC) Infiltration Correlate with Tumor Infiltrating Lymphocytes, Cancer Immunity, and Better Survival in Triple Negative Breast Cancer (TNBC) More Strongly than Conventional Dendritic Cell (cDC)
por: Oshi, Masanori, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8qeibm53crsdsl9gl13u2eho8n