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Clonal architectures predict clinical outcome in clear cell renal cell carcinoma

The genetic landscape of clear cell renal cell carcinoma (ccRCC) had been investigated extensively but its evolution patterns remained unclear. Here we analyze the clonal architectures of 473 patients from three different populations. We find that the mutational signatures vary substantially across...

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Detalles Bibliográficos
Autores principales:	Huang, Yi, Wang, Jiayin, Jia, Peilin, Li, Xiangchun, Pei, Guangsheng, Wang, Changxi, Fang, Xiaodong, Zhao, Zhongming, Cai, Zhiming, Yi, Xin, Wu, Song, Zhang, Baifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423009/ https://www.ncbi.nlm.nih.gov/pubmed/30886153 http://dx.doi.org/10.1038/s41467-019-09241-7

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