Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome

Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare genetic disorder for which no cure exists. The disease is characterized by premature aging and inevitable death in adolescence due to cardiovascular complications. Most HGPS patients carry a heterozygous de novo LMNA c.1824C > T mut...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorado, Beatriz, Pløen, Gro Grunnet, Barettino, Ana, Macías, Alvaro, Gonzalo, Pilar, Andrés-Manzano, María Jesús, González-Gómez, Cristina, Galán-Arriola, Carlos, Alfonso, José Manuel, Lobo, Manuel, López-Martín, Gonzalo J., Molina, Antonio, Sánchez-Sánchez, Raúl, Gadea, Joaquín, Sánchez-González, Javier, Liu, Ying, Callesen, Henrik, Filgueiras-Rama, David, Ibáñez, Borja, Sørensen, Charlotte Brandt, Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423020/
https://www.ncbi.nlm.nih.gov/pubmed/30911407
http://dx.doi.org/10.1038/s41421-019-0084-z

Ejemplares similares

Ejemplares similares