Cargando…
Neutrophils and Close Relatives in the Hypoxic Environment of the Tuberculous Granuloma: New Avenues for Host-Directed Therapies?
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) is one of the most prevalent lung infections of humans and kills ~1.7 million people each year. TB pathophysiology is complex with a central role played by granuloma where a delicate balance takes place to both constrain bacilli and preve...
Autores principales: | Remot, Aude, Doz, Emilie, Winter, Nathalie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423059/ https://www.ncbi.nlm.nih.gov/pubmed/30915076 http://dx.doi.org/10.3389/fimmu.2019.00417 |
Ejemplares similares
-
Neutrophils Encompass a Regulatory Subset Suppressing T Cells in Apparently Healthy Cattle and Mice
por: Rambault, Marion, et al.
Publicado: (2021) -
In the Thick of It: Formation of the Tuberculous Granuloma and Its Effects on Host and Therapeutic Responses
por: Cronan, Mark R.
Publicado: (2022) -
CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy
por: Doz-Deblauwe, Émilie, et al.
Publicado: (2019) -
Granulomas and Inflammation: Host-Directed Therapies for Tuberculosis
por: Ndlovu, Hlumani, et al.
Publicado: (2016) -
Targeting Molecular Inflammatory Pathways in Granuloma as Host-Directed Therapies for Tuberculosis
por: Guler, Reto, et al.
Publicado: (2021)