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[Ru(bpy)(2)(NO)SO(3)](PF(6)), a Nitric Oxide Donating Ruthenium Complex, Reduces Gout Arthritis in Mice

Monosodium urate crystals (MSU) deposition induces articular inflammation known as gout. This disease is characterized by intense articular inflammation and pain by mechanisms involving the activation of the transcription factor NFκB and inflammasome resulting in the production of cytokines and oxid...

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Detalles Bibliográficos
Autores principales:	Rossaneis, Ana C., Longhi-Balbinot, Daniela T., Bertozzi, Mariana M., Fattori, Victor, Segato-Vendrameto, Carina Z., Badaro-Garcia, Stephanie, Zaninelli, Tiago H., Staurengo-Ferrari, Larissa, Borghi, Sergio M., Carvalho, Thacyana T., Bussmann, Allan J. C., Gouveia, Florêncio S., Lopes, Luiz G. F., Casagrande, Rubia, Verri, Waldiceu A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423075/ https://www.ncbi.nlm.nih.gov/pubmed/30914954 http://dx.doi.org/10.3389/fphar.2019.00229

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