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The WNT/β-catenin signaling inhibitor XAV939 enhances the elimination of LNCaP and PC-3 prostate cancer cells by prostate cancer patient lymphocytes in vitro
Upregulated Wnt/β-catenin signaling is associated with increased cancer cell resistance and cancer cell-elicited immunosuppression. In non-neoplastic immune cells, upregulated Wnt/β-catenin is, however, associated with either immunosuppression or immunostimulation. Therefore, it is difficult to pred...
Autores principales: | Stakheev, Dmitry, Taborska, Pavla, Strizova, Zuzana, Podrazil, Michal, Bartunkova, Jirina, Smrz, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423115/ https://www.ncbi.nlm.nih.gov/pubmed/30886380 http://dx.doi.org/10.1038/s41598-019-41182-5 |
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