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DNA polymerase ι is acetylated in response to S(N)2 alkylating agents
DNA polymerase iota (Polι) belongs to the Y-family of DNA polymerases that are involved in DNA damage tolerance through their role in translesion DNA synthesis. Like all other Y-family polymerases, Polι interacts with proliferating cell nuclear antigen (PCNA), Rev1, ubiquitin and ubiquitinated-PCNA...
Autores principales: | McIntyre, Justyna, Sobolewska, Aleksandra, Fedorowicz, Mikolaj, McLenigan, Mary P., Macias, Matylda, Woodgate, Roger, Sledziewska-Gojska, Ewa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423139/ https://www.ncbi.nlm.nih.gov/pubmed/30886224 http://dx.doi.org/10.1038/s41598-019-41249-3 |
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