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A new reporter design based on DNA origami nanostructures for quantification of short oligonucleotides using microbeads
The DNA origami technique has great potential for the development of brighter and more sensitive reporters for fluorescence based detection schemes such as a microbead-based assay in diagnostic applications. The nanostructures can be programmed to include multiple dye molecules to enhance the measur...
Autores principales: | Choi, Youngeun, Schmidt, Carsten, Tinnefeld, Philip, Bald, Ilko, Rödiger, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423227/ https://www.ncbi.nlm.nih.gov/pubmed/30886341 http://dx.doi.org/10.1038/s41598-019-41136-x |
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