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A new reporter design based on DNA origami nanostructures for quantification of short oligonucleotides using microbeads

The DNA origami technique has great potential for the development of brighter and more sensitive reporters for fluorescence based detection schemes such as a microbead-based assay in diagnostic applications. The nanostructures can be programmed to include multiple dye molecules to enhance the measur...

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Detalles Bibliográficos
Autores principales: Choi, Youngeun, Schmidt, Carsten, Tinnefeld, Philip, Bald, Ilko, Rödiger, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423227/
https://www.ncbi.nlm.nih.gov/pubmed/30886341
http://dx.doi.org/10.1038/s41598-019-41136-x

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