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MiR-125a enhances self-renewal, lifespan, and migration of murine hematopoietic stem and progenitor cell clones
Expansion of hematopoietic stem cells (HSCs) is a ‘holy grail’ of regenerative medicine, as successful stem cell transplantations depend on the number and quality of infused HSCs. Although many attempts have been pursued to either chemically or genetically increase HSC numbers, neither clonal analys...
Autores principales: | Wojtowicz, Edyta Ewa, Broekhuis, Mathilde Johanna Christina, Weersing, Ellen, Dinitzen, Alexander, Verovskaya, Evgenia, Ausema, Albertina, Ritsema, Martha, Zwart, Erik, de Haan, Gerald, Bystrykh, Leonid V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423273/ https://www.ncbi.nlm.nih.gov/pubmed/30886165 http://dx.doi.org/10.1038/s41598-019-38503-z |
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