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Bone morphogenetic protein-7 retards cell subculture-induced senescence of human nucleus pulposus cells through activating the PI3K/Akt pathway

Background: Allogeneic disc cell is the main cellular resource in tissue engineering (TE)-based strategy to retard disc degeneration. However, the accessible disc cells often exhibit senescent phenotype when they are subcultured in vitro. Hence, alleviating senescence of human disc cells during cell...

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Detalles Bibliográficos
Autores principales: Gong, Chen, Pan, Wei, Hu, Wei, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423306/
https://www.ncbi.nlm.nih.gov/pubmed/30787052
http://dx.doi.org/10.1042/BSR20182312