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Bone morphogenetic protein-7 retards cell subculture-induced senescence of human nucleus pulposus cells through activating the PI3K/Akt pathway
Background: Allogeneic disc cell is the main cellular resource in tissue engineering (TE)-based strategy to retard disc degeneration. However, the accessible disc cells often exhibit senescent phenotype when they are subcultured in vitro. Hence, alleviating senescence of human disc cells during cell...
Autores principales: | Gong, Chen, Pan, Wei, Hu, Wei, Chen, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423306/ https://www.ncbi.nlm.nih.gov/pubmed/30787052 http://dx.doi.org/10.1042/BSR20182312 |
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