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Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice
Besides causing mild hand, foot and mouth infections, Enterovirus A71 (EV-A71) is associated with neurological complications and fatality. With concerns about rising EV-A71 virulence, there is an urgency for more effective vaccines. The live attenuated vaccine (LAV) is a more valuable vaccine as it...
Autores principales: | Yee, Pinn Tsin Isabel, Tan, Soon Hao, Ong, Kien Chai, Tan, Kuan Onn, Wong, Kum Thong, Hassan, Sharifah Syed, Poh, Chit Laa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423319/ https://www.ncbi.nlm.nih.gov/pubmed/30886246 http://dx.doi.org/10.1038/s41598-019-41285-z |
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