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Mitral valve repair based on intraoperative objective measurement

In this paper, we propose a very innovative designed system that enables optimal length adjustment during transapical neochordae implantation for mitral valve repair, increasing accuracy and reproducibility of neochordae length adjustment. Also, such a new device allowed real-time measurement and re...

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Autores principales: Grinberg, Daniel, Le, Minh-Quyen, Kwon, Young Joon, Fernandez, Miguel A., Audigier, David, Ganet, Florent, Capsal, Jean-Fabien, Obadia, Jean François, Cottinet, Pierre-Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423320/
https://www.ncbi.nlm.nih.gov/pubmed/30886234
http://dx.doi.org/10.1038/s41598-019-41173-6
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author Grinberg, Daniel
Le, Minh-Quyen
Kwon, Young Joon
Fernandez, Miguel A.
Audigier, David
Ganet, Florent
Capsal, Jean-Fabien
Obadia, Jean François
Cottinet, Pierre-Jean
author_facet Grinberg, Daniel
Le, Minh-Quyen
Kwon, Young Joon
Fernandez, Miguel A.
Audigier, David
Ganet, Florent
Capsal, Jean-Fabien
Obadia, Jean François
Cottinet, Pierre-Jean
author_sort Grinberg, Daniel
collection PubMed
description In this paper, we propose a very innovative designed system that enables optimal length adjustment during transapical neochordae implantation for mitral valve repair, increasing accuracy and reproducibility of neochordae length adjustment. Also, such a new device allowed real-time measurement and recording of chordae tension, producing original physiological data. To the best of our knowledge, the tension of chordae had never been measured previously as precisely, especially in in vivo human clinical trials. Preliminary experimental data have been collected on 10 selected patients, giving us the opportunity to assess for the first time the tension applied on the chordae implanted in beating human hearts. The final goal of our measuring device is to provide reliable objective intraoperative data to improve the understanding of changes occurring after mitral valve repair (MVR). This novel measuring instrument may bring change in the paradigm of MVR by allowing repair with strong objective and quantitative, instead of qualitative anatomical analysis.
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spelling pubmed-64233202019-03-26 Mitral valve repair based on intraoperative objective measurement Grinberg, Daniel Le, Minh-Quyen Kwon, Young Joon Fernandez, Miguel A. Audigier, David Ganet, Florent Capsal, Jean-Fabien Obadia, Jean François Cottinet, Pierre-Jean Sci Rep Article In this paper, we propose a very innovative designed system that enables optimal length adjustment during transapical neochordae implantation for mitral valve repair, increasing accuracy and reproducibility of neochordae length adjustment. Also, such a new device allowed real-time measurement and recording of chordae tension, producing original physiological data. To the best of our knowledge, the tension of chordae had never been measured previously as precisely, especially in in vivo human clinical trials. Preliminary experimental data have been collected on 10 selected patients, giving us the opportunity to assess for the first time the tension applied on the chordae implanted in beating human hearts. The final goal of our measuring device is to provide reliable objective intraoperative data to improve the understanding of changes occurring after mitral valve repair (MVR). This novel measuring instrument may bring change in the paradigm of MVR by allowing repair with strong objective and quantitative, instead of qualitative anatomical analysis. Nature Publishing Group UK 2019-03-18 /pmc/articles/PMC6423320/ /pubmed/30886234 http://dx.doi.org/10.1038/s41598-019-41173-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Grinberg, Daniel
Le, Minh-Quyen
Kwon, Young Joon
Fernandez, Miguel A.
Audigier, David
Ganet, Florent
Capsal, Jean-Fabien
Obadia, Jean François
Cottinet, Pierre-Jean
Mitral valve repair based on intraoperative objective measurement
title Mitral valve repair based on intraoperative objective measurement
title_full Mitral valve repair based on intraoperative objective measurement
title_fullStr Mitral valve repair based on intraoperative objective measurement
title_full_unstemmed Mitral valve repair based on intraoperative objective measurement
title_short Mitral valve repair based on intraoperative objective measurement
title_sort mitral valve repair based on intraoperative objective measurement
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423320/
https://www.ncbi.nlm.nih.gov/pubmed/30886234
http://dx.doi.org/10.1038/s41598-019-41173-6
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