Structure and Molecular Mechanism of ER Stress Signaling by the Unfolded Protein Response Signal Activator IRE1

The endoplasmic reticulum (ER) is an important site for protein folding and maturation in eukaryotes. The cellular requirement to synthesize proteins within the ER is matched by its folding capacity. However, the physiological demands or aberrations in folding may result in an imbalance which can le...

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Detalles Bibliográficos
Autores principales: Adams, Christopher J., Kopp, Megan C., Larburu, Natacha, Nowak, Piotr R., Ali, Maruf M. U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423427/
https://www.ncbi.nlm.nih.gov/pubmed/30931312
http://dx.doi.org/10.3389/fmolb.2019.00011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423427/
https://www.ncbi.nlm.nih.gov/pubmed/30931312
http://dx.doi.org/10.3389/fmolb.2019.00011

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