Cargando…

Hepatoprotective Effects of Silymarin on Liver Injury via Irisin Upregulation and Oxidative Stress Reduction in Rats with Type 2 Diabetes

BACKGROUND: Diabetes is one of the most prevalent metabolic diseases. Irisin (FNDC5 protein) is involved in the new strategy of combating type 2 diabetes. In the liver, the antidiabetic mechanism of silymarin at the molecular level is unknown. This study investigated the effects of silymarin on iris...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kheiripour, Nejat, Karimi, Jamshid, Khodadadi, Iraj, Tavilani, Heidar, Taghi Goodarzi, Mohammad, Hashemnia, Mohammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Iranian Journal of Medical Sciences 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423431/ https://www.ncbi.nlm.nih.gov/pubmed/30936597

Ejemplares similares

Methanolic Extract of Dill Leaves Inhibits AGEs Formation and Shows Potential Hepatoprotective Effects in CCl(4) Induced Liver Toxicity in Rat
por: Oshaghi, Ebrahim Abbasi, et al.
Publicado: (2017)

Aminoguanidine partially prevents the reduction in liver pyruvate kinase activity in diabetic rats
por: Majd, Alimohammad Amiri, et al.
Publicado: (2014)

Effects of curcumin and metformin on oxidative stress and apoptosis in heart tissue of type 1 diabetic rats
por: Naghdi, Atefeh, et al.
Publicado: (2022)

Effect of dill tablet (Anethum graveolens L) on antioxidant status and biochemical factors on carbon tetrachloride-induced liver damage on rat
por: Oshaghi, Ebrahim Abbasi, et al.
Publicado: (2016)

Ameliorative Effects of Nilotinib on CCl4 Induced Liver Fibrosis Via Attenuation of RAGE/HMGB1 Gene Expression and Oxidative Stress in Rat
por: Khanjarsim, Vahid, et al.
Publicado: (2017)

Dill-normalized liver lipid accumulation, oxidative stress, and low-density lipoprotein receptor levels in high cholesterol fed hamsters
por: Abbasi-Oshaghi, Ebrahim, et al.
Publicado: (2018)

The Role of Anethum graveolens L. (Dill) in the Management of Diabetes
por: Goodarzi, Mohammad Taghi, et al.
Publicado: (2016)

Aqueous Extract of Anethum Graveolens L. has Potential Antioxidant and Antiglycation Effects
por: Oshaghi, Ebrahim Abbasi, et al.
Publicado: (2016)

Circulating Betatrophin Levels Are Associated with the Lipid Profile in Type 2 Diabetes
por: Ghasemi, Hassan, et al.
Publicado: (2015)

Resveratrol-Dependent Down-regulation of Receptor for Advanced Glycation End-products and Oxidative Stress in Kidney of Rats With Diabetes
por: Moridi, Heresh, et al.
Publicado: (2015)

Favorable effects of Anethum graveolens on liver oxidative stress and cholesterol 7 alpha-hydroxylase levels in non-alcoholic fatty liver disease (NAFLD) rat models
por: Abbasi, Ebrahim, et al.
Publicado: (2021)

Kiwifruit effect on adipose tissue cell size and cholesteryl ester transfer protein gene expression in high-fat diet fed Golden Syrian hamsters
por: Zaherijamil, Zahra, et al.
Publicado: (2019)

Favorable effects of dill tablets and Ocimum basilicum L. extract on learning, memory, and hippocampal fatty acid composition in hypercholesterolemic rats
por: Heshami, Neda, et al.
Publicado: (2021)

Lipid Lowering Effects of Hydroalcoholic Extract of Anethum graveolens L. and Dill Tablet in High Cholesterol Fed Hamsters
por: Abbasi Oshaghi, Ebrahim, et al.
Publicado: (2015)

Downregulation of Sirt1 is correlated to upregulation of p53 and increased apoptosis in epicardial adipose tissue of patients with coronary artery disease
por: Khanahmadi, Mahdieh, et al.
Publicado: (2020)

Propofol Attenuates Toxic Oxidative Stress by CCl(4) in Liver Mitochondria and Blood in Rat
por: Ranjbar, Akram, et al.
Publicado: (2014)

Diabetes and COVID-19: Mechanism of pneumonia, treatment strategy and vaccine
por: Abbasi, Ebrahim, et al.
Publicado: (2021)

Gene Polymorphism of Matrix Metalloproteinase 9 in Asthenozoospermic Male Subjects
por: Mohagheghi, Sina, et al.
Publicado: (2018)

Activity of Matrix Metalloproteinase 2 and 9 in Follicular Fluid and Seminal Plasma and Its Relation to Embryo Quality and Fertilization Rate
por: Atabakhsh, Mojgan, et al.
Publicado: (2018)

Genistein Induces Apoptosis and Inhibits Proliferation of HT29 Colon Cancer Cells
por: Shafiee, Gholamreza, et al.
Publicado: (2016)

Hepatoprotective effects of silymarin in management of liver injury caused by tuberculosis treatment
por: Lee, Yeong Yeh, et al.
Publicado: (2023)

Serum levels of lycopene, beta-carotene, and retinol and their correlation with sperm DNA damage in normospermic and infertile men
por: Ghyasvand, Taiebeh, et al.
Publicado: (2015)

Hepatoprotective Property of Oral Silymarin is Comparable to N-Acetyl Cysteine in Acetaminophen Poisoning
por: Kazemifar, Amir Mohammad, et al.
Publicado: (2012)

Association between seminal plasma neopterin and oxidative stress in male infertility: A case-control study
por: Ghiasvand, Tayebeh, et al.
Publicado: (2018)

Construction of Plasmid Insulin Gene Vector Containing Metallothionein IIA (pcDNAMTChIns) and Carbohydrate Response Element (ChoRE), and Its Expression in NIH3T3 Cell Line
por: Piri, Hossein, et al.
Publicado: (2012)

NLRP3-inflammasome activation is associated with epithelial-mesenchymal transition and progression of colorectal cancer
por: Marandi, Yasser, et al.
Publicado: (2021)

Targeting silymarin for improved hepatoprotective activity through chitosan nanoparticles
por: Gupta, Swati, et al.
Publicado: (2014)

The Association of Mitochondrial Translocator Protein and Voltage-Dependent Anion Channel-1 in Granulosa Cells with Estradiol Levels and Presence of Immature Follicles in Polycystic Ovary Syndrome
por: Mazloomi, Sahar, et al.
Publicado: (2022)

Synthesis, characterization and hepatoprotective effect of silymarin phytosome nanoparticles on ethanol-induced hepatotoxicity in rats
por: Gohari Mahmoudabad, Arezoo, et al.
Publicado: (2023)

Investigating the impact of silymarin on liver oxidative injury
por: Jamalian, Mohammad, et al.
Publicado: (2020)

Evaluating the effect of arachidonic acid and eicosapentaenoic acid on induction of adipogenesis in human adipose-derived stem cells
por: Mostoli, Rezvan, et al.
Publicado: (2020)

Hepatoprotective activity of silymarin encapsulation against hepatic damage in albino rats
por: Mukhtar, Shanza, et al.
Publicado: (2021)

Hepatoprotective effect of silymarin on fructose induced nonalcoholic fatty liver disease in male albino wistar rats
por: Mengesha, Tewodros, et al.
Publicado: (2021)

Irisin Contributes to the Hepatoprotection of Dexmedetomidine during Intestinal Ischemia/Reperfusion
por: Fan, Xin, et al.
Publicado: (2019)

Hepatoprotective Effects of Silybum marianum (Silymarin) and Glycyrrhiza glabra (Glycyrrhizin) in Combination: A Possible Synergy
por: Rasool, Mahmood, et al.
Publicado: (2014)

Hepatoprotective and renoprotective effects of silymarin against salinomycin-induced toxicity in adult rabbits
por: Ghonaim, Ahmed H., et al.
Publicado: (2022)

Hepatoprotective activities of picroliv, curcumin, and ellagic acid compared to silymarin on carbon-tetrachloride-induced liver toxicity in mice
por: Girish, C., et al.
Publicado: (2012)

Correction to: Hepatoprotective effect of silymarin on fructose induced nonalcoholic fatty liver disease in male albino wistar rats
por: Mengesha, Tewodros, et al.
Publicado: (2021)

Resveratrol attenuates visfatin and vaspin genes expression in adipose tissue of rats with type 2 diabetes
por: Asadi, Soheila, et al.
Publicado: (2015)

Hepatoprotective Effect of Silymarin (Silybum marianum) on Hepatotoxicity Induced by Acetaminophen in Spontaneously Hypertensive Rats
por: Freitag, Abel Felipe, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_iltd1vrdjh09b5933m6lr04t2p