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Mutation of IDH1 aggravates the fatty acid-induced oxidative stress in HCT116 cells by affecting the mitochondrial respiratory chain

Increasing evidence has indicated that mutations of isocitrate dehydrogenase 1/2 (IDH1/2) contribute to the metabolic reprogramming of cancer cells; however their functions in lipid metabolism remain unknown. In the present study, the parental and IDH1 (R132H/+) mutant HCT116 cells were treated with...

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Detalles Bibliográficos
Autores principales:	Li, Sheng, Sun, Chao, Gu, Yu, Gao, Xing, Zhao, Yuanlin, Yuan, Yuan, Zhang, Feng, Hu, Peizhen, Liang, Weihua, Cao, Kaiyu, Zhang, Jin, Wang, Zhe, Ye, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423594/ https://www.ncbi.nlm.nih.gov/pubmed/30720071 http://dx.doi.org/10.3892/mmr.2019.9903

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