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Synthesis of the aglycon of scorzodihydrostilbenes B and D
Benzyl- and methyl-protected 2,4-dihydroxyacetophenones are added under ruthenium catalysis to 4-methoxy- and 3,4-dimethoxystyrene in a completely regioselective manner. Thus, oxygenated dihydrostilbenes are obtained that feature the skeleton of scorzodihydrostilbenes – antioxidative agents that wer...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Beilstein-Institut
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423597/ https://www.ncbi.nlm.nih.gov/pubmed/30931002 http://dx.doi.org/10.3762/bjoc.15.56 |
| _version_ | 1783404556055478272 |
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| author | Weimann, Katja Braun, Manfred |
| author_facet | Weimann, Katja Braun, Manfred |
| author_sort | Weimann, Katja |
| collection | PubMed |
| description | Benzyl- and methyl-protected 2,4-dihydroxyacetophenones are added under ruthenium catalysis to 4-methoxy- and 3,4-dimethoxystyrene in a completely regioselective manner. Thus, oxygenated dihydrostilbenes are obtained that feature the skeleton of scorzodihydrostilbenes – antioxidative agents that were recently isolated from Scorzonera radiata. Selective deprotection liberates the corresponding phenols, among them the aglycon of scorzodihydrostilbenes B and D. |
| format | Online Article Text |
| id | pubmed-6423597 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-64235972019-03-29 Synthesis of the aglycon of scorzodihydrostilbenes B and D Weimann, Katja Braun, Manfred Beilstein J Org Chem Full Research Paper Benzyl- and methyl-protected 2,4-dihydroxyacetophenones are added under ruthenium catalysis to 4-methoxy- and 3,4-dimethoxystyrene in a completely regioselective manner. Thus, oxygenated dihydrostilbenes are obtained that feature the skeleton of scorzodihydrostilbenes – antioxidative agents that were recently isolated from Scorzonera radiata. Selective deprotection liberates the corresponding phenols, among them the aglycon of scorzodihydrostilbenes B and D. Beilstein-Institut 2019-03-06 /pmc/articles/PMC6423597/ /pubmed/30931002 http://dx.doi.org/10.3762/bjoc.15.56 Text en Copyright © 2019, Weimann and Braun https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Weimann, Katja Braun, Manfred Synthesis of the aglycon of scorzodihydrostilbenes B and D |
| title | Synthesis of the aglycon of scorzodihydrostilbenes B and D |
| title_full | Synthesis of the aglycon of scorzodihydrostilbenes B and D |
| title_fullStr | Synthesis of the aglycon of scorzodihydrostilbenes B and D |
| title_full_unstemmed | Synthesis of the aglycon of scorzodihydrostilbenes B and D |
| title_short | Synthesis of the aglycon of scorzodihydrostilbenes B and D |
| title_sort | synthesis of the aglycon of scorzodihydrostilbenes b and d |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423597/ https://www.ncbi.nlm.nih.gov/pubmed/30931002 http://dx.doi.org/10.3762/bjoc.15.56 |
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