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Lipoxin A4 Methyl Ester Reduces Early Brain Injury by Inhibition of the Nuclear Factor Kappa B (NF-κB)-Dependent Matrix Metallopeptidase 9 (MMP-9) Pathway in a Rat Model of Intracerebral Hemorrhage

BACKGROUND: Intracerebral hemorrhage (ICH) is associated with inflammation and disruption of the blood-brain barrier (BBB). Lipoxin A4 methyl ester (LXA4 ME), is a stable synthetic analog of lipoxin with anti-inflammatory properties. This study aimed to investigate the effects of LXA4 ME in a rat mo...

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Detalles Bibliográficos
Autores principales: Song, Yaqi, Yang, Ying, Cui, Ying, Gao, Junling, Wang, Kaijie, Cui, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423737/
https://www.ncbi.nlm.nih.gov/pubmed/30855024
http://dx.doi.org/10.12659/MSM.915119