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Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison

OBJECTIVE: For patients with cystic fibrosis, the imaging of the pancreas is of crucial importance for the early detection of pancreatic carcinoma. Comparative studies between Magnetic Resonance Imaging (MRI) and sonographic pancreas sonography are not yet available. The aim of the study was to comp...

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Autores principales: Kloth, Christopher, Fabricius, Dorit, Wendlik, Inka, Schmidt, Stefan Andreas, Pfahler, Matthias, Lormes, Elisabeth, Beer, Meinrad, Kratzer, Wolfgang, Schmidberger, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423810/
https://www.ncbi.nlm.nih.gov/pubmed/30885270
http://dx.doi.org/10.1186/s13104-019-4193-4
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author Kloth, Christopher
Fabricius, Dorit
Wendlik, Inka
Schmidt, Stefan Andreas
Pfahler, Matthias
Lormes, Elisabeth
Beer, Meinrad
Kratzer, Wolfgang
Schmidberger, Julian
author_facet Kloth, Christopher
Fabricius, Dorit
Wendlik, Inka
Schmidt, Stefan Andreas
Pfahler, Matthias
Lormes, Elisabeth
Beer, Meinrad
Kratzer, Wolfgang
Schmidberger, Julian
author_sort Kloth, Christopher
collection PubMed
description OBJECTIVE: For patients with cystic fibrosis, the imaging of the pancreas is of crucial importance for the early detection of pancreatic carcinoma. Comparative studies between Magnetic Resonance Imaging (MRI) and sonographic pancreas sonography are not yet available. The aim of the study was to compare MRI, sonography and point-shearwave elastography (pSWE). A total of 19 patients were included (10 male, 9 female; age 29.7 ± 14.3 years) in the study. Ultrasonography with pSWE and contrast enhanced MRI with MRCP were performed. RESULTS: Significant differences between measurements of pancreatic body were registered in MRI with 1.4 ± 0.6 cm vs 1.0 ± 0.4 cm in ultrasound (p = 0.049), however not for pancreatic head and tail. In 10/19 patients (52.6%) pancreatic parenchyma did not show in MRI because of complete lipomatous transformation, but could be detected in ultrasound. pSWE-values showed no significant differences between the full and partial fatty transformation in pancreatic head (p = 0.968), body (p = 0.657) and tail (p = 0.840). pSWE-values did not correlate with measured signal intensity in T1w flash (p = 0.930, r = 0.025) and T2w HASTE sequences (p = 0.152, r = − 0.375). In patients with CF ultrasound is superior to MRI for displaying full fibro-fatty parenchymal transformation, pancreatic duct. Ultrasound elastography did not provide additional clinical relevant information. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-019-4193-4) contains supplementary material, which is available to authorized users.
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spelling pubmed-64238102019-03-28 Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison Kloth, Christopher Fabricius, Dorit Wendlik, Inka Schmidt, Stefan Andreas Pfahler, Matthias Lormes, Elisabeth Beer, Meinrad Kratzer, Wolfgang Schmidberger, Julian BMC Res Notes Research Note OBJECTIVE: For patients with cystic fibrosis, the imaging of the pancreas is of crucial importance for the early detection of pancreatic carcinoma. Comparative studies between Magnetic Resonance Imaging (MRI) and sonographic pancreas sonography are not yet available. The aim of the study was to compare MRI, sonography and point-shearwave elastography (pSWE). A total of 19 patients were included (10 male, 9 female; age 29.7 ± 14.3 years) in the study. Ultrasonography with pSWE and contrast enhanced MRI with MRCP were performed. RESULTS: Significant differences between measurements of pancreatic body were registered in MRI with 1.4 ± 0.6 cm vs 1.0 ± 0.4 cm in ultrasound (p = 0.049), however not for pancreatic head and tail. In 10/19 patients (52.6%) pancreatic parenchyma did not show in MRI because of complete lipomatous transformation, but could be detected in ultrasound. pSWE-values showed no significant differences between the full and partial fatty transformation in pancreatic head (p = 0.968), body (p = 0.657) and tail (p = 0.840). pSWE-values did not correlate with measured signal intensity in T1w flash (p = 0.930, r = 0.025) and T2w HASTE sequences (p = 0.152, r = − 0.375). In patients with CF ultrasound is superior to MRI for displaying full fibro-fatty parenchymal transformation, pancreatic duct. Ultrasound elastography did not provide additional clinical relevant information. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-019-4193-4) contains supplementary material, which is available to authorized users. BioMed Central 2019-03-18 /pmc/articles/PMC6423810/ /pubmed/30885270 http://dx.doi.org/10.1186/s13104-019-4193-4 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Kloth, Christopher
Fabricius, Dorit
Wendlik, Inka
Schmidt, Stefan Andreas
Pfahler, Matthias
Lormes, Elisabeth
Beer, Meinrad
Kratzer, Wolfgang
Schmidberger, Julian
Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison
title Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison
title_full Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison
title_fullStr Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison
title_full_unstemmed Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison
title_short Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison
title_sort diagnostic accuracy of mri with mrcp and b-mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423810/
https://www.ncbi.nlm.nih.gov/pubmed/30885270
http://dx.doi.org/10.1186/s13104-019-4193-4
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