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Comparing efficacy and safety between Naldebain(®) and intravenous patient-controlled analgesia with fentanyl for pain management post-laparotomy: study protocol for a randomized controlled, non-inferior trial
BACKGROUND: A long-acting prodrug of nalbuphine, nalbuphine sebacate, has been developed for meeting the unmet medical need of long-acting analgesics. Naldebain(®) (nalbuphine sebacate) has been developed as a new premedication for postoperative pain management. The primary objective of this study i...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423831/ https://www.ncbi.nlm.nih.gov/pubmed/30885242 http://dx.doi.org/10.1186/s13063-019-3260-4 |