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Identifying and exploiting gene-pathway interactions from RNA-seq data for binary phenotype
BACKGROUND: RNA sequencing (RNA-seq) technology has identified multiple differentially expressed (DE) genes associated to complex disease, however, these genes only explain a modest part of variance. Omnigenic model assumes that disease may be driven by genes with indirect relevance to disease and b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423879/ https://www.ncbi.nlm.nih.gov/pubmed/30890140 http://dx.doi.org/10.1186/s12863-019-0739-7 |